The history of present-day Cross River State stretches back centuries before colonial rule. The region was home to numerous peoples and communities including the Efik, Ejagham, Bekwarra, Bette, Boki, Yakurr, Mbembe, Yala, Igede, Bahumono, Efut and several other groups. These societies developed distinctive political systems, languages, religious traditions, economic practices and forms of artistic expression.
The lower Cross River basin became an important area of commerce. Communities traded agricultural products, fish, salt, palm produce, forest products, livestock and manufactured goods. River systems provided transportation and connected inland communities with coastal trading centres.
Among the most historically prominent centres was Old Calabar, associated principally with Efik merchant communities. Through riverine trade networks, Calabar developed commercial relationships with European traders along the West African coast. The region became particularly important in the Atlantic trade from the seventeenth and eighteenth centuries onward.
In the interior, communities developed independent political institutions. Some were organised around kingship, councils of elders, age-grade systems and clan structures. The diversity of Cross River's peoples means that there was never one political kingdom controlling the entire territory.